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Lecture 8 — Cardiac electrophysiology

Phase 0: rapid depolarization via fast Na⁺ channels.

Phase 1: transient K⁺ efflux, early repolarization.

Phase 2: plateau — Ca²⁺ influx balances K⁺ efflux.

Phase 3: repolarization as K⁺ channels dominate.

Phase 4: resting potential maintained by Na⁺/K⁺ ATPase.

SA node sets rate through funny current (If).

Refractory period prevents tetany in cardiac muscle.

Lecture 8 — Cardiac electrophysiology

Phase 0: rapid depolarization via fast Na⁺ channels.

Phase 1: transient K⁺ efflux, early repolarization.

Phase 2: plateau — Ca²⁺ influx balances K⁺ efflux.

Phase 3: repolarization as K⁺ channels dominate.

Phase 4: resting potential maintained by Na⁺/K⁺ ATPase.

SA node sets rate through funny current (If).

Refractory period prevents tetany in cardiac muscle.

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